The remarkable achievements made in medical science during and after COVID-19 offer an unprecedented opportunity for transformative change to improve population health—subject to equitable global access.

Equitable access to novel medical technologies will require i) a suitable global political compact reconsidering power relationships between the Global North and the Global South, ii) an end-to-end architecture for adoption, iii) a research and development paradigm directed to the common good, and iv) strengthened health service delivery capacity.